Detalhe da pesquisa
1.
Computational redesign of cytochrome P450 CYP102A1 for highly stereoselective omeprazole hydroxylation by UniDesign.
J Biol Chem
; 299(8): 105050, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37451479
2.
Regulatory variants in TCF7L2 are associated with thoracic aortic aneurysm.
Am J Hum Genet
; 108(9): 1578-1589, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34265237
3.
Bicuspid Aortic Valve-Associated Regulatory Regions Reveal GATA4 Regulation and Function During Human-Induced Pluripotent Stem Cell-Based Endothelial-Mesenchymal Transition-Brief Report.
Arterioscler Thromb Vasc Biol
; 43(2): 312-322, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36519469
4.
Single-Molecule Spatial Transcriptomics of Human Thoracic Aortic Aneurysms Uncovers Calcification-Related CARTPT-Expressing Smooth Muscle Cells.
Arterioscler Thromb Vasc Biol
; 43(12): 2285-2297, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37823268
5.
Lp-PLA2 (Lipoprotein-Associated Phospholipase A2) Deficiency Lowers Cholesterol Levels and Protects Against Atherosclerosis in Rabbits.
Arterioscler Thromb Vasc Biol
; 43(1): e11-e28, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36412196
6.
An Asian-specific MPL genetic variant alters JAK-STAT signaling and influences platelet count in the population.
Hum Mol Genet
; 30(9): 836-842, 2021 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33693786
7.
Exosomes from adipose-derived stem cells alleviate myocardial infarction via microRNA-31/FIH1/HIF-1α pathway.
J Mol Cell Cardiol
; 162: 10-19, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34474073
8.
hiPSC Modeling of Lineage-Specific Smooth Muscle Cell Defects Caused by TGFBR1A230T Variant, and Its Therapeutic Implications for Loeys-Dietz Syndrome.
Circulation
; 144(14): 1145-1159, 2021 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34346740
9.
RNA sequencing reveals perivascular adipose tissue plasticity in response to angiotensin II.
Pharmacol Res
; 178: 106183, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35306139
10.
Endothelial TFEB (Transcription Factor EB) Improves Glucose Tolerance via Upregulation of IRS (Insulin Receptor Substrate) 1 and IRS2.
Arterioscler Thromb Vasc Biol
; 41(2): 783-795, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33297755
11.
New Insight Into Metformin-Induced Cholesterol-Lowering Effect Crosstalk Between Glucose and Cholesterol Homeostasis via ChREBP (Carbohydrate-Responsive Element-Binding Protein)-Mediated PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Regulation.
Arterioscler Thromb Vasc Biol
; 41(4): e208-e223, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33535788
12.
Untargeted metabolomics identifies succinate as a biomarker and therapeutic target in aortic aneurysm and dissection.
Eur Heart J
; 42(42): 4373-4385, 2021 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34534287
13.
Improving the genome assembly of rabbits with long-read sequencing.
Genomics
; 113(5): 3216-3223, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34051323
14.
Cyclodextrin Prevents Abdominal Aortic Aneurysm via Activation of Vascular Smooth Muscle Cell Transcription Factor EB.
Circulation
; 142(5): 483-498, 2020 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32354235
15.
TMAVA, a Metabolite of Intestinal Microbes, Is Increased in Plasma From Patients With Liver Steatosis, Inhibits γ-Butyrobetaine Hydroxylase, and Exacerbates Fatty Liver in Mice.
Gastroenterology
; 158(8): 2266-2281.e27, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32105727
16.
Perivascular Adipose Tissue Regulates Vascular Function by Targeting Vascular Smooth Muscle Cells.
Arterioscler Thromb Vasc Biol
; 40(5): 1094-1109, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32188271
17.
In Vitro Lineage-Specific Differentiation of Vascular Smooth Muscle Cells in Response to SMAD3 Deficiency: Implications for SMAD3-Related Thoracic Aortic Aneurysm.
Arterioscler Thromb Vasc Biol
; 40(7): 1651-1663, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32404006
18.
Clopidogrel Resistance in a Murine Model of Diet-Induced Obesity Is Mediated by the Interleukin-1 Receptor and Overcome With DT-678.
Arterioscler Thromb Vasc Biol
; 40(6): 1533-1542, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32268786
19.
Apolipoprotein CIII Deficiency Protects Against Atherosclerosis in Knockout Rabbits.
Arterioscler Thromb Vasc Biol
; 40(9): 2095-2107, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32757647
20.
BAF60a Deficiency in Vascular Smooth Muscle Cells Prevents Abdominal Aortic Aneurysm by Reducing Inflammation and Extracellular Matrix Degradation.
Arterioscler Thromb Vasc Biol
; 40(10): 2494-2507, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32787523